New publications from collaborations

 

Februrary 2022 - Article: The Clinical Concept of LTDpathy...

Februrary 2022 - Article: The Clinical Concept of LTDpathy...

Long-term depression at parallel fibers-Purkinje cells is essential for cerebellar motor learning and control. Recent progress in ataxiology has identified dysregulation in the pathophysiology of certain types of immune-mediated cerebellar ataxias. Our hypothesis underlines for the first time a potential role of LTD dysfunction in the pathogenesis of the prodromal symptoms of CAs. 

Februrary 2022 - Article: Glial Fibrillary Acidic Protein Autoimmunity

Februrary 2022 - Article: Glial Fibrillary Acidic Protein Autoimmunity

Thhis article reports the clinical, biological, imaging features, and the clinical course of a French cohort of patients with glial fibrillar acidic protein (GFAP) autoantibodies.

December 2021: Current Status of Biomarkers in...

December 2021: Current Status of Biomarkers in...

Ciano-Petersen and al. present an overview of the biomarkers described so far in antiNMDAR encephalitis, from clinical and paraclinical features identified during the routine diagnostic workup, to advanced molecular biomarkers that could improve our understanding of anti-NMDAR encephalitis pathophysiology and lead to the development of novel targeted-treatments 

November 2021: Abdominal Segmental Myoclonus...

November 2021: Abdominal Segmental Myoclonus...

Khatib and al. present an 86-year-old man presented with continuous movements of the abdominal wall (abdominal segmental myoclonus mimicking a belly dancer), gait unsteadiness, progressive cognitive deficit, episodic symptomatic hypotension, and diaphoresis for 2 months

July 2021 - Letter: Spinal cord tractopathy in paraneoplastic anti-CV2/CRMP5...

July 2021 - Letter: Spinal cord tractopathy in paraneoplastic anti-CV2/CRMP5...

An adenocarcinoma of the lung was diagnosed by biopsy in a 68-year-old man in August 2018. Two weeks later, the patient reported walking difficulties and bladder incontinence....

June 2021 - Letter: Secondary antibodies detection in LGI1...

June 2021 - Letter: Secondary antibodies detection in LGI1...

Autoimmune encephalitis is usually suspected on the basis of clinical and paraclinical criteria and confirmed by the identification of specific antibodies in serum and/or CSF samples.This letter presents a case of an anti LGI-1 encephalitis where a diagnosis was made during follow-up.

May 2021- Article: Cerebrospinal Fluid IL-17A Could Predict...

May 2021- Article: Cerebrospinal Fluid IL-17A Could Predict...

This articles reports the concentrations of CSF sIL-2R, IL-6, IL-8, IL-10 and IL-17A and correlates it with acute disease severity and the 1-year outcome in non-NMDAR AE.

April 2021 - Article: Missense variants in DPYSL5 cause a neurodevelopmental

April 2021 - Article: Missense variants in DPYSL5 cause a neurodevelopmental

This study adds DPYSL5 to the list of genes implicated in brain malformation and in neurodevelopmental disorders.

 

Februrary 2021 - Article: Relationship between serum NMDA...

Februrary 2021 - Article: Relationship between serum NMDA...

This article from our collaboration with T Pollak and al proposes a description of the role of ANMDA antibodies in psychosis onset and response to antipsychotic treatment.

October 2020 - Article: Psychiatric symptoms in anti glutamic...

October 2020 - Article: Psychiatric symptoms in anti glutamic...

The description of the neuropsychiatric spectrum of anti-GAD LE and its specificities aims to improve our understanding of this entity, and may lead to earlier diagnosis as well as better outcome.

September 2020 - Article: Clinical features, prognostic, and antibody...

September 2020 - Article: Clinical features, prognostic, and antibody...

BETPSY members participated to this scientific paper which aims is to clinically characterize patients with anti-metabotropic glutamate receptor (mGluR)1 encephalitis, identify prognostic factors, and study the IgG subclasses and effects of antibodies on neuronal mGluR1 clusters.