List of BETPSY publications

 

BETPSY Project

 

Biomarkers in autoimmune EncephaliTis and

Paraneoplastic neurological SYndromes

 

 

Scientific articles 

Campetella et al. Corticospinal tract hyperintensity in patients with LGI1-antibody encephalitis and other central nervous system disorders with neuroglial antibodies. J Neuroimmunol. 2024DOI: 10.1016/j.jneuroim.2024.578346(WP2)

Lamblin et al. Nonparaneoplastic Autoimmune Encephalitis With GABABR Antibodies. Neurol Neuroimmunol Neuroinflamm. 2024. doi:10.1212/NXI.0000000000200229 (WP2)

Campetella et al. Predictors and Clinical Characteristics of Relapses in LGI1-Antibody Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2024 . doi: 10.1212/NXI.0000000000200228. (WP2)

 

Farina et al. Mononeuritis multiplex following immune checkpoint inhibitors in malignant pleural mesothelioma. Frontiers. 2024.  https://doi.org/10.3389/fneur.2024.1338899 (WP2)

 

Villagran-Garcia et al. Revisiting anti-Hu paraneoplastic autoimmunity: phenotypic characterization and cancer diagnosis. Brain Commun. 2023. 10.1093/braincomms/fcad247 (WP2)

 

Farina A. et al. Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity, Brain Commun, Volume 5, Issue 3, 2023, fcad169, https://doi.org/10.1093/braincomms/fcad169 (WP2)

 

Bartley C. et al. Detection of High-Risk Paraneoplastic Antibodies against TRIM9 and TRIM67 Proteins. Ann Neurol. 2023. doi: 10.1002/ana.26776 (WP2)

 

Theuriet J. et al. Peripheral nervous system involvement accompanies central nervous system involvement in anti-glial fibrillary acidic protein (GFAP) antibody-related disease. J Neurol. 2023 ;270(11):5545-5560. doi: 10.1007/s00415-023-11908-7 (WP2)

 

Vogrig et al. Different Genetic Signatures of Small-Cell Lung Cancer Characterize Anti-GABABR and Anti-Hu Paraneoplastic Neurological Syndromese. Ann Neurol. 2023. https://doi.org/10.1002/ana.26784. (WP4)

 

Cluse F et al. Trigeminal Nerve Involvement in Bulbar-Onset Anti-IgLON5 Disease. Neurol Neuroimmunol Neuroinflamm. 2023 . doi: 10.1212/NXI.0000000000200153. (WP2)

 

Alentorn A et al. Spatial and Ecological Factors Modulate the Incidence of Anti-NMDAR Encephalitis—A Systematic Review. Neurol Neuroimmunol Biomedecine. 2023.  https://doi.org/10.3390/biomedicines11061525. (WP2)

 

Schiff P et al. Anti-LGI1 Encephalitis With Co-occurring IgLON5 Antibodies: Clinical Features and Human Leukocyte Antigen Haplotypes. Neurol Neuroimmunol Neuroinflamm. 2023. doi: 10.1212/NXI.0000000000200126. (WP2)

 

Ciano-Petersen NL et al. Prognostic Value of Persistent CSF Antibodies at 12 Months in Anti-NMDAR Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2023. doi: 10.1212/NXI.0000000000200108.  (WP2)

 

Vilaseca, A. et al. The expanding spectrum of antibody-associated cerebellar ataxia: report of two new cases of anti-AP3B2 ataxia. J Neurol. 2023. https://doi.org/10.1007/s00415-023-11732-z (WP2)

 

Flet-Berliac., et al. Long-term outcome of paediatric anti-N-methyl-D-aspartate receptor encephalitis. Develomental medicine & child neurology 2023.  https://doi.org/10.1111/dmcn.15429 (WP2)

 

Faure F., et al. A Pilot Study to Develop Paraneoplastic Cerebellar Degeneration Mouse Model. The Cerebellum 2023. https://doi.org/10.1007/s12311-023-01524-6 (WP2)

 

Khatib L., et al. Autoimmune Cerebellar Ataxia Associated withAnti‑Glutamate Receptor δ2 Antibodies: a Rare but Treatable Entity. The Cerebellum. 2023. https://doi.org/10.1007/s12311-023-01523-7 (WP2)

 

Farina A., et al. Anti-Hu Antibodies in Patients With Neurologic Side Effects of Immune Checkpoint Inhibitors. Neurol Neuroimmunol Neuroinflamm. 2023DOI: https://doi.org/10.1212/NXI.0000000000200058 (WP2)

 

Vabanesi M., et al. SOX1 antibody-related paraneoplastic neurological syndromes: clinical correlates and assessment of laboratory diagnostic techniques. Journal of neurology. 202310.1007/s00415-022-11523-y (WP2)

 

Benoit J, et al. Early-Stage Contactin-Associated Protein-like 2 Limbic Encephalitis Clues for Diagnosis. Neurol Neuroimmunol Neuroinflamm. 2022https://doi.org/10.1212/NXI.0000000000200041 (WP2)

 

Moritz C, et al. Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies. Front. Immunol. 2022. https://doi.org/10.3389/fimmu.2022.972161 (WP2)

 

Villagran-Garcia M et al. Paraneoplastic neurological syndromes associated with renal or bladder cancer: case series and PRISMA-IPD systematic review. J Neurol. 2022. doi: 10.1007/s00415-022-11356-9 (WP2)

 

Peter E, Do LD, et al. Cerebellar Ataxia With Anti-DNER Antibodies: Outcomes and Immunologic Features. Neurol Neuroimmunol Neuroinflamm. 2022doi: 10.1212/NXI.0000000000200018 (WP2)

 

Peter E, Treilleux I, et al. Immune and Genetic Signatures of Breast Carcinomas Triggering Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration. Neurol Neuroimmunol Neuroinflamm. 2022. 10.1212/NXI.0000000000200015 (WP4)

 

Peris Sempre V, Muñiz-Castrillo S, et al. Human Leukocyte Antigen Association Study Reveals DRB1*04:02 Effects Additional to DRB1*07:01 in Anti-LGI1 Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2022. DOI: https://doi.org/10.1212/NXI.0000000000001140 (WP3)

Lardeux P, and al. Core cerebrospinal fuid biomarker profile in anti‑LGI1 encephalitisJournal of neurology. 2022. https://doi.org/10.1007/s00415-021-10642-2 (WP2)

Tholance Y, Antoine JC, et al. Anti-FGFR3 antibody epitopes are functional sites and correlate with the neuropathy patternJournal of neuroimmunology. 2021. https://doi.org/10.1007/s00415-021-10870-6 (WP2)

Vogrig A, Péricart S, et al. Immunopathogenesis and proposed clinical score for identifying Kelch-like protein-11 encephalitisBrain Communications. 2021. https://doi.org/10.1093/braincomms/fcab185 (WP2)

Do L, Moritz C, et al. Argonaute Autoantibodies as Biomarkers in Autoimmune Neurologic DiseasesNeurol Neuroimmunol Neuroinflamm. 2021. DOI: https://doi.org/10.1212/NXI.0000000000001032 (WP2)

Muñiz-Castrillo S, Hedou J, et al. Distinctive clinical presentation and pathogenic specificities of anti-AK5 encephalitis. Brain, 2021; awab153, https://doi.org/10.1093/brain/awab153 (WP3)

Muñiz‑Castrillo S, Haesebaert J et al. Clinical and Prognostic Value of Immunogenetic Characteristics in Anti-LGI1 Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2021. DOI: https://doi.org/10.1212/NXI.0000000000000974 (WP3)

Muñiz‑Castrillo S, Vogrig A et al. Familial autoimmunity in neurological patients with GAD65 antibodies: an interview-based study. Journal of neurology. 2021. https://doi.org/10.1007/s00415-021-10424-w (WP3)

Moritz C, et al. CIDP Antibodies Target Junction Proteins and Identify Patient Subgroups. Neurol Neuroimmunol Neuroinflamm. 2021. doi.org/10.1212/NXI.0000000000000944 (WP2)

Vogrig A, et al. Cranial Nerve Disorders Associated with Immune Checkpoint Inhibitors. Neurology. 2020. doi.org/10.1212/WNL.0000000000011340 (WP2)

Moritz C et al. Proper definition of the set of autoantibody-targeted antigens relies on appropriate reference group selection. New biotechnology. 2020. doi.org/10.1016/j.nbt.2020.08.007 (WP2)

Hébert J, Riche B et al. Epidemiology of paraneoplastic neurologic syndromes and autoimmune encephalitides in France. Neurol Neuroimmunol Neuroinflamm. 2020; 7 (6). https://doi.org/10.1212/NXI.0000000000000883 (WP1-WP6)

Muñiz‑Castrillo S, Joubert B, et al. Anti-CASPR2 clinical phenotypes correlate with HLA et immunological features. J Neurol Neurosurg Psychiatry. 2020; 0:1–9. doi.org/10.1136/jnnp-2020-323226 (WP3)

 

Muñiz‑Castrillo S, Vogrig A, Joubert B, et al. Transient Neurological Symptoms Preceding Cerebellar Ataxia with Glutamic Acid Decarboxylase Antibodies. Cerebellum. 2020; 19 715-721. https://doi.org/10.1007/s12311-020-01159-x (WP2)

 

Vogrig A, Muñiz‑Castrillo S, Joubert B, et al. Central nervous system complications associated with immune checkpoint inhibitors. J Neurol Neurosurg Psychiatry. 2020; . doi: 10.1136/jnnp-2020-323212 (WP2)

 

Simard C, Vogrig A, Joubert B, et al. Clinical spectrum and diagnostic pitfalls of neurologic syndromes with Ri antibodies. Neurol Neuroimmunol Neuroinflamm. 2020; 7:e699. DOI: https://doi.org/10.1212/NXI.0000000000000699 (WP2)

 

Déchelotte B, Muñiz‑Castrillo S, Joubert B, et al. Diagnostic yield of commercial immunodots to diagnose paraneoplastic neurological syndromes. Neurol Neuroimmunol Neuroinflamm. 2020; 7(3):e701. https://doi.org/10.1212/NXI.0000000000000701 (WP2)

 

Muñiz‑Castrillo S, Ambati A, Dubois V, et al. Primary DQ effect in the association between HLA and neurological syndromes with anti-GAD65 antibodies. J Neurol. 2020; 267:1906-1911. http://dx.doi.org/10.1007/s00415-020-09782-8 (WP3)

 

Vogrig. A, Gigli, G.L., Segatti, S. et al. Epidemiology of paraneoplastic neurological syndromes: a population-based study. J Neurol. 2020; 267: 26-35http://dx.doi.org/10.1007/s00415-019-09544-1 (WP2)

 

Joubert, B., Belbezier, A., Haesebaert, J. et al. Long-term outcomes in temporal lobe epilepsy with glutamate decarboxylase antibodies. J Neurology. 2020. https://doi.org/10.1007/s00415-020-09807-2 (WP2)

 

 

Reviews

Villagrán-García M et al. Dysautonomia in anti-Hu paraneoplastic neurological syndromes. J Neurol 2024. doi: 10.1007/s00415-024-12278-4. (WP2)

 

Vilaseca A et al. Neurological autoimmunity in melanoma patients: a comparison between those exposed and non-exposed to immune checkpoint inhibitors. J Neurol. 202410.1007/s00415-024-12252-0 (WP2)

 

Muñiz-Castrillo, Sergio et al. Genetic predisposition to autoimmune encephalitis and paraneoplastic neurological syndromes. Current Opinion in Neurology. 2024 DOI: 10.1097/WCO.0000000000001263 (WP3)

 

Farina A et al. Neurological adverse events of immune checkpoint inhibitors and the development of paraneoplastic neurological syndromes. Lancet Neurol. 2024; 23: 81–94. doi.10.1016/S1474-4422(23)00369-1.(WP2)

 

Vogrig et al. Sudden unexpected death in epilepsy and ictal asystole in patients with autoimmune encephalitis: a systematic review. Neurological Sciences. 2024. https://doi.org/10.1007/s10072-023-07280-z (WP2) 

 

Villagrán-García M et al. Autonomic nervous system involvement in autoimmune encephalitis and paraneoplastic neurological syndromes. Rev Neurol. 2023. doi: 10.1016/j.neurol.2023.12.001 (WP2)

 

Farina A et al. Neurological adverse events of immune checkpoint inhibitors: An update of clinical presentations, diagnosis, and management. Revue neurologique. 2023. https://doi.org/10.1016/j.neurol.2023.03.003 (WP2)

 

Campérat L et al. Autoimmune neuromyotonia. Curr Opin Neurol. 2022. 10.1097/WCO.0000000000001104. (WP2)

 

Antoine JC. Sensory neuronopathies, diagnostic criteria and causes. Curr Opin Neurol. 2022. Volume 4, Issue 4, 2022, fcac196, 10.1097/WCO.0000000000001105. (WP2)

 

Ciano-Petersen NL et al. Cytokine dynamics and targeted immunotherapies in autoimmune encephalitis. Brain communications. 2022. Volume 4, Issue 4, 2022, fcac196, https://doi.org/10.1093/braincomms/fcac196 (WP2)

 

Vaišvilas M, Ciano-Petersen NL, et al. Paraneoplastic encephalitis: clinically based approach on diagnosis and management. Postgrad Med J. 2022 -141766doi: 10.1136/postgradmedj-2022-141766 (WP2)

 

Muñiz‑Castrillo S, Vogrig A, et al. Novelties in Autoimmune and Paraneoplastic Cerebellar Ataxias: Twenty Years of ProgressesThe Cerebellum. 2022.https://doi.org/10.1007/s12311-021-01363-3 (WP2)


Ciano-Petersen N, Muñiz‑Castrillo S, et al. Immunomodulation in the acute phase of autoimmune encephalitisRevue neurologique. 2022. https://doi.org/10.1016/j.neurol.2021.12.001 (WP2)

 

Ciano-Petersen N et al. Current Status of Biomarkers in Anti-N-Methyl-D-Aspartate Receptor Encephalitis. Int J Mol Sci. 2021. doi: 10.3390/ijms222313127 (WP2)


Binks S, Uy C, Honnorat J, Irani S. Paraneoplastic neurological syndromes: a practical approach to diagnosis and management. Pract Neurol. 2021http://dx.doi.org/10.1136/practneurol-2021-003073 (WP2)

 

Graus F, Vogrig A, Muñiz-Castrillo S, et al. Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes. Neurol Neuroimmunol Neuroinflamm. 2021. DOI: 10.1212/NXI.0000000000001014 (WP2)

 

Vogrig A, Muñiz-Castrillo S, et al. How to diagnose and manage neurological toxicities of immune checkpoint inhibitors: an updateJournal of neurology. 2021. https://doi.org/10.1007/s00415-021-10870-6 (WP2)

 

Fels E, Muñiz‑Castrillo S, et al. Role of LGI1 protein in synaptic transmission: From physiology to pathologyNeurobiology of disease. 2021. doi: 10.1016/j.nbd.2021.105537 (WP2)

 

Wiendl H, Gross C, et al. Fundamental mechanistic insights from rare but paradigmatic neuroimmunological diseasesA Systematic Review. Nature Reviews Neurology 2021. https://doi.org/10.1038/s41582-021-00496-7 (WP5)

 

Marini A, Bernardini A, et al. Neurologic Adverse Events of Immune Checkpoint Inhibitors: A Systematic ReviewNeurology 2021. DOI: https://doi.org/10.1212/WNL.0000000000011795 (WP2)

 

Mitoma H, Honnorat J et al. Fundamental Mechanisms of Autoantibody-Induced Impairments on Ion Channels and Synapses in Immune-Mediated Cerebellar Ataxias. Int. J. Mol. Sci. 2020, 21, 4936https://doi:10.3390/ijms21144936 (WP2)

 

Muñiz-Castrillo S, et al. Diagnostic des encéphalites auto-immunes. Pratique Neurologique – FMC 2020. doi.org/10.1016/j.praneu.2020.08.006 (WP2) 

 

Vogrig A, Muñiz‑Castrillo S, Desestret V. Pathophysiology of paraneoplastic and autoimmune encephalitis: genes, infections, and checkpoint inhibitors. Ther Adv Neurol Disord. 2020; 13:1-15https://doi.org/10.1177/1756286420932797 (WP2)

  

Yshii L, Bost C, Liblau R. Immunological Bases of Paraneoplastic Cerebellar Degeneration and Therapeutic Implications. Frontiers in immunology. 2020; 11:911 https://doi.org/10.3389/fimmu.2020.00991 (WP5)

 

Muñiz‑Castrillo S, Vogrig A, Honnorat J. Associations between HLA and autoimmune neurological diseases with autoantibodies. Autoimmun Highlights. 2020; 11:2. https://doi.org/10.1186/s13317-019-0124-6 (WP3)

 

 

Letters

Mongay-Ochoa N, Vogrig A, Muñiz‑Castrillo S, Honnorat J. Anti‑Hu‑associated paraneoplastic syndromes triggered by immune‑checkpoint inhibitor treatment. J Neurol. 2020https://doi.org/10.1007/s00415-020-09940-y (WP2)

 

Vogrig A, Muñiz‑Castrillo S, Honnorat J. Value of onconeural antibodies in checkpoint inhibitor-related toxicities. Ann Neurol. 2020. https://doi.org/10.1002/ana.25764 (WP2)

 

 

Others

Quero K, Joubert B, et al. Paraneoplastic cerebellar degeneration associated with Hodgkin Lymphoma: A french retrospective cohort. Abstract EP1140.<span style="font-size: 12pt; color: